Editorial

Failed Total Shoulder Arthroplasty

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Failed Total Shoulder Arthroplasty

This illustration was commissioned for Arthroscopically Assisted Conversion of Total Shoulder Arthroplasty to Hemiarthroplasty With Glenoid Bone Grafting by Surena Namdari, MD, MSc; and David Glaser, MD for publication in ORTHOPEDICS October 2011 issue (ORTHOPEDICS November 2011;34(11):862). Aseptic loosening of the glenoid component after total shoulder arthroplasty presents a considerable treatment challenge in the setting of substantial glenoid bone loss.  Glenoid component explantation and bone grafting of defects has become a common methods of recreating bone stock in hopes of...

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Natural Killer Cells

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Natural Killer Cells

This illustration was created for a feature article in the October 2011 issue of the Washington University in St. Louis Alumni Magazine article by Steve Kohler. “Professor Wayne Yokoyama, MD, long intrigued by the function of natural killer (NK) cells, has shown that NK cells, using a “licensing strategy,” are vitally important elements of the immune system. In 2010, on the occasion of accepting the Lee C. Howley Sr. Prize for his pioneering arthritis research, Wayne M. Yokoyama, MD, told his audience that real advances in science do not come from the close application of previously...

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HIF-1 Inhibition in Mitochondria

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HIF-1 Inhibition in Mitochondria

HIF-1 Inhibition in Mitochondria

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Patellar Instability

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Patellar Instability

According to Dr. Hu Xu of the Department of Orthopedics, Xijing Hospital, proximal soft-tissue realignment is the main surgical intervention for recurrent patellar instability. In recent years, all-inside arthroscopic procedures or mini-open surgeries comes to replace traditional operations which have more associated morbidity and poor cosmetic results. In this article (ORTHOPEDICS July 2011;34(7):524), Xu and his colleagues report a very simple and all-inside arthroscopic technique for the operative treatment of recurrent patellar instability. Using two epidural needles in several steps and...

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Alzheimer’s Disease

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Alzheimer’s Disease

Recently, Fairman Studios was asked to create another cover piece for the American Academy of Family Physicians on the Treatment of Alzheimer’s Disease. Alzheimer’s disease (AD) is the most common form of dementia, affecting one-third of Americans over age 85.  It is characterized by progressive memory loss and cognitive  decline.  Amyloid plaque accumulation, neurofibrillary tau tangles and depletion of acetylcholine are among the pathologic manifestations of AD.  While there are no clearly effective preventive modalities currently, hypertension treatment, omega-3 fatty acid...

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The Genetic Journey

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The Genetic Journey

This informational graphic visually summarizes the diverse topics of genetic science that researchers are investigating —such as DNA markers, cellular pathways, chromosomes, mosquito genomes, biostatistics and ethics—to find new ways to improve global health.  Through a visually stimulating portrayal of a wide variety of current genetic research areas, this spread exhibits significant scientific investigations impact on human medicine span from the microscopic to the macroscopic. The spread conveys the 12 specific genetic research areas described and summarized in captions and expressed...

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