Recently, Fairman Studios was asked to create another cover piece for the American Academy of Family Physicians on the Treatment of Alzheimer’s Disease. Alzheimer’s disease (AD) is the most common form of dementia, affecting one-third of Americans over age 85. It is characterized by progressive memory loss and cognitive decline. Amyloid plaque accumulation, neurofibrillary tau tangles and depletion of acetylcholine are among the pathologic manifestations of AD. While there are no clearly effective preventive modalities currently, hypertension treatment, omega-3 fatty acid supplementation, physical activity and cognitive engagement demonstrate modest potential.